PT-141 (bremelanotide) 10mg

PT-141 (Bremelanotide)

PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (alpha-MSH). Unlike PDE5 inhibitors that act on vascular smooth muscle, PT-141 activates melanocortin receptors in the central nervous system, making it the first compound studied that addresses arousal through a neurological mechanism of action rather than a purely vascular one.

Mechanism of Action

PT-141 primarily activates melanocortin-4 receptors (MC4R) in the hypothalamus and limbic system - brain regions involved in sexual arousal, desire, and motivation. MC4R activation triggers downstream dopaminergic signaling pathways associated with reward and arousal responses. This central mechanism of action distinguishes PT-141 from vascular-acting compounds and has generated significant research interest in the neuroscience of sexual function and motivation.

Key Research Applications

Published peer-reviewed studies have investigated this compound in the context of melanocortin-4 receptor pharmacology, central nervous system arousal pathways, sexual function and desire mechanisms, dopaminergic reward signaling, hypothalamic-limbic circuit activation, and melanocortin system biology. Researchers continue to explore its potential across multiple experimental models, with a growing body of literature supporting further investigation.

What You Receive

(1) Vial containing 10mg lyophilized powder. Requires reconstitution with bacteriostatic water (sold separately). Syringes not included.

Storage

Store lyophilized (freeze-dried) peptide at -20C for long-term stability. After reconstitution with bacteriostatic water, refrigerate at 2-8C and use within 30 days. Protect from light and avoid repeated freeze-thaw cycles.

Quality Assurance

Every batch is independently tested by a third-party laboratory using HPLC and mass spectrometry to verify 99%+ purity. A Certificate of Analysis (COA) is included with your order. Produced in a GMP-certified, ISO-compliant facility with full batch traceability.

Note: This product is sold strictly for research, laboratory, and analytical purposes only. Not intended for human consumption. All researchers are responsible for ensuring compliance with applicable institutional, local, and federal regulations.