Snap-8 10mg

Snap-8 (Acetyl Octapeptide-3)

Snap-8, also known as Acetyl Octapeptide-3, is a synthetic octapeptide that modulates the SNARE complex - the molecular machinery responsible for neurotransmitter vesicle fusion and release at neuromuscular junctions. It is an extended analog of Argireline (Acetyl Hexapeptide-3), with two additional amino acids that research suggests may enhance its activity.

Mechanism of Action

Snap-8 competitively inhibits the formation of the SNARE complex by mimicking the N-terminal end of SNAP-25 (synaptosomal-associated protein of 25 kDa). The SNARE complex is required for synaptic vesicle docking and fusion with the presynaptic membrane, a prerequisite for acetylcholine release. By interfering with this complex, Snap-8 reduces the magnitude of acetylcholine release at the neuromuscular junction, resulting in reduced muscle contraction intensity. This mechanism has been studied extensively in cosmetic and dermatological research as a topical approach to reducing expression lines.

Key Research Applications

Published peer-reviewed studies have investigated this compound in the context of SNARE complex modulation, neuromuscular junction pharmacology, acetylcholine release dynamics, muscle contraction reduction, expression line formation, and topical peptide delivery models. Researchers continue to explore its potential across multiple experimental models, with a growing body of literature supporting further investigation.

What You Receive

(1) Vial containing 10mg lyophilized powder. Requires reconstitution with bacteriostatic water (sold separately). Syringes not included.

Storage

Store lyophilized (freeze-dried) peptide at -20C for long-term stability. After reconstitution with bacteriostatic water, refrigerate at 2-8C and use within 30 days. Protect from light and avoid repeated freeze-thaw cycles.

Quality Assurance

Every batch is independently tested by a third-party laboratory using HPLC and mass spectrometry to verify 99%+ purity. A Certificate of Analysis (COA) is included with your order. Produced in a GMP-certified, ISO-compliant facility with full batch traceability.

Note: This product is sold strictly for research, laboratory, and analytical purposes only. Not intended for human consumption. All researchers are responsible for ensuring compliance with applicable institutional, local, and federal regulations.