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DSIP 5mg

DSIP is a naturally occurring neuropeptide found in the brain and cerebrospinal fluid. It interacts with various endocrine and neurochemical systems to:

  • Regulate sleep by promoting delta (slow-wave) sleep patterns

  • Influence the hypothalamic-pituitary axis

  • Potentially modulate NMDA receptor activity

  • Reduce stress-related hormone release (e.g., cortisol)

YOU RECEIVE: (1) Peptide bottle (freeze dried powder, not liquid)   *Peptides need to be mixed with bacteriostatic water to research **NOT included- Syringes (all peptides are research products) **Bacteriostatic water (all peptides are research products)
$79.00
In stock

In stock

Same-day shipping by 3pm ET, Mon–Fri 2-day express delivery via FedEx or UPS
=99% purity
CoA enclosed
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SKU: DSIP
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DSIP (Delta Sleep-Inducing Peptide)

DSIP is a naturally occurring neuropeptide first isolated from rabbit brain tissue in 1977. Composed of nine amino acids (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu), it was originally identified for its role in promoting delta-wave sleep patterns in EEG studies. Subsequent research has revealed a much broader range of neuroregulatory functions.

Mechanism of Action

DSIP modulates multiple neurotransmitter systems and neuroendocrine pathways. It has been shown to influence the hypothalamic-pituitary axis, modulate cortisol and ACTH release patterns, and interact with opioid and serotonergic systems. Its sleep-promoting effects appear to work by normalizing disrupted sleep architecture rather than inducing sedation - a key distinction from conventional sedative compounds. Research also suggests DSIP may influence stress-response pathways and pain perception through its interactions with endogenous opioid systems.

Key Research Applications

Published peer-reviewed studies have investigated this compound in the context of sleep architecture and delta-wave activity, circadian rhythm regulation, stress response and HPA axis modulation, pain perception pathways, neuroendocrine regulation, and withdrawal models. Researchers continue to explore its potential across multiple experimental models, with a growing body of literature supporting further investigation.

What You Receive

(1) Vial containing 5mg lyophilized powder. Requires reconstitution with bacteriostatic water (sold separately). Syringes not included.

Storage

Store lyophilized (freeze-dried) peptide at -20C for long-term stability. After reconstitution with bacteriostatic water, refrigerate at 2-8C and use within 30 days. Protect from light and avoid repeated freeze-thaw cycles.

Quality Assurance

Every batch is independently tested by a third-party laboratory using HPLC and mass spectrometry to verify 99%+ purity. A Certificate of Analysis (COA) is included with your order. Produced in a GMP-certified, ISO-compliant facility with full batch traceability.

Note: This product is sold strictly for research, laboratory, and analytical purposes only. Not intended for human consumption. All researchers are responsible for ensuring compliance with applicable institutional, local, and federal regulations.

For research use only. This product is sold for research, laboratory, and analytical purposes only. Not intended for human consumption.

Product specifications

Purity=99% (HPLC verified)
FormLyophilized (freeze-dried) powder
TestingIndependent HPLC, mass spectrometry, endotoxin
DocumentationBatch-matched Certificate of Analysis
SKUDSIP

Storage & handling guidelines

Proper storage is essential to maintain peptide integrity and maximize shelf life. Follow these guidelines for best results in your research workflow.

Before reconstitution Store at −20°C in a freezer. Stable for up to 24 months when sealed and frozen. Avoid temperature fluctuation.
After reconstitution Refrigerate at 2–8°C. Use within 7 days for optimal purity. Reconstitute only with bacteriostatic water.
Important notes Avoid freeze-thaw cycles. Protect from direct light. Discard if cloudy, discolored, or precipitated.

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DSIP 5mg
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